| Primary Identifier | MGI:2443639 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 320234 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables protein homodimerization activity. Involved in cilium disassembly; detection of light stimulus involved in visual perception; and positive regulation of smoothened signaling pathway. Acts upstream of or within post-embryonic retina morphogenesis in camera-type eye and retinal rod cell development. Located in axoneme and photoreceptor inner segment. Is expressed in several structures, including cerebral cortex ventricular layer; ganglia; nucleus pulposus; spinal cord; and vibrissa. Used to study retinitis pigmentosa. Orthologous to human CCDC66 (coiled-coil domain containing 66). PHENOTYPE: Mice homozygous for a null mutation display slowly progressing photoreceptor degeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
