| Primary Identifier | MGI:1921991 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 74741 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity. Involved in insulin receptor signaling pathway; positive regulation of D-glucose transmembrane transport; and positive regulation of vesicle fusion. Acts upstream of or within positive regulation of D-glucose import; protein localization to plasma membrane; and vesicle fusion. Located in plasma membrane. Orthologous to human C2CD5 (C2 calcium dependent domain containing 5). PHENOTYPE: Mice homozygous for a knock-out allele have altered catecholamine levels, exhibit energy imbalance and obesity due to impaired fat browning, lipolysis, fatty acid oxidation and thermogenesis, and develop insulin resistance and impaired glucose metabolism in response to high-fat diet feeding. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
