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Protein Coding Gene : Med21 mediator complex subunit 21

Primary Identifier  MGI:1347064 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  108098
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within blastocyst development and somatic stem cell population maintenance. Part of mediator complex. Is expressed in tibialis anterior and tongue. Orthologous to human MED21 (mediator complex subunit 21).
PHENOTYPE: Embryos homozygous for a targeted null mutation die at the blastocyst stage. [provided by MGI curators]
  • synonyms:
  • MGI:1289181,
  • D6Ertd782e,
  • MGI:2141415,
  • Med21,
  • AI449604,
  • MGI:1913295,
  • Srb7,
  • D19234,
  • expressed sequence AI449604,
  • expressed sequence D19234,
  • mediator complex subunit 21,
  • DNA segment, Chr 6, ERATO Doi 782, expressed,
  • RIKEN cDNA 0610007L03 gene,
  • Surb7,
  • 0610007L03Rik,
  • MGI:2141792,
  • SRB7 (suppressor of RNA polymerase B) homolog (S. cerevisiae)

Features --> Cross References

Genome

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0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For