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Protein Coding Gene : Med21 mediator complex subunit 21
Primary Identifier  MGI:1347064 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  108098
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within blastocyst development and somatic stem cell population maintenance. Part of mediator complex. Is expressed in tibialis anterior and tongue. Orthologous to human MED21 (mediator complex subunit 21).
PHENOTYPE: Embryos homozygous for a targeted null mutation die at the blastocyst stage. [provided by MGI curators]
  • synonyms:
  • 0610007L03Rik,
  • MGI:1913295,
  • Med21,
  • Srb7,
  • RIKEN cDNA 0610007L03 gene,
  • expressed sequence D19234,
  • Surb7,
  • SRB7 (suppressor of RNA polymerase B) homolog (S. cerevisiae),
  • DNA segment, Chr 6, ERATO Doi 782, expressed,
  • MGI:2141415,
  • expressed sequence AI449604,
  • AI449604,
  • MGI:1289181,
  • D6Ertd782e,
  • MGI:2141792,
  • D19234,
  • mediator complex subunit 21
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