Primary Identifier | MGI:2443575 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 320204 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-lysine N-methyltransferase activity. Involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase and peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrial matrix. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; respiratory system; and thymus. Orthologous to human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased oxygen consumption rate and heat production under ketogenic conditions and enhanced cold tolerance during fasting. [provided by MGI curators] |