Primary Identifier | MGI:2179720 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 232790 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables collagen receptor activity. Acts upstream of or within Fc-gamma receptor signaling pathway; multinuclear osteoclast differentiation; and positive regulation of bone resorption. Located in cell surface. Is expressed in testis. Orthologous to human OSCAR (osteoclast associated Ig-like receptor). PHENOTYPE: Bone marrow macrophage from mice homozygous for a knock-out allele exhibit impaired osteoclast differentiation. [provided by MGI curators] |