| Primary Identifier | MGI:1889007 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 57776 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity and volume-sensitive chloride channel activity. Involved in L-glutamate transmembrane transport. Acts upstream of or within several processes, including Notch signaling pathway; filopodium assembly; and stem cell proliferation. Located in filopodium membrane; filopodium tip; and smooth endoplasmic reticulum membrane. Is active in membrane and synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human TTYH1 (tweety family member 1). PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation with arrest before the blastocyst stage and mitotic failure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
