Primary Identifier | MGI:107613 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 16156 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity and interleukin-11 receptor binding activity. Acts upstream of or within positive regulation of cell population proliferation. Located in cytoplasm. Is expressed in liver. Orthologous to human IL11 (interleukin 11). PHENOTYPE: Homozygous null females are infertile and show reduced bone mass, suppressed bone formation response to mechanical loading, increased systemic adiposity, glucose intolerance and insulin resistance. [provided by MGI curators] |