Primary Identifier | MGI:1925141 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 77891 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable anaphase-promoting complex binding activity and ubiquitin conjugating enzyme activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; exit from mitosis; and protein polyubiquitination. Predicted to be part of anaphase-promoting complex. Predicted to be active in nucleus. Orthologous to human UBE2S (ubiquitin conjugating enzyme E2 S). PHENOTYPE: Mice homozygous for a null allele display reduced susceptibility to viral infection, female infertility, and arrest of female meiosis. [provided by MGI curators] |