Primary Identifier | MGI:3605641 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 232813 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GABA receptor binding activity and ionotropic glutamate receptor binding activity. Involved in several processes, including gamma-aminobutyric acid receptor clustering; positive regulation of long-term synaptic potentiation; and regulation of signaling receptor activity. Located in asymmetric, glutamatergic, excitatory synapse and postsynaptic density. Is active in glutamatergic synapse and postsynaptic specialization membrane. Is expressed in central nervous system; craniocervical region bone; dorsal root ganglion; rib; and tail mesenchyme. Orthologous to human SHISA7 (shisa family member 7). PHENOTYPE: Homozygous knockout results in impaired expression of contextual fear memory. [provided by MGI curators] |