| Primary Identifier | MGI:2444763 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 232854 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in microautophagy and regulation of proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within cardiac muscle hypertrophy; negative regulation of cell growth involved in cardiac muscle cell development; and negative regulation of protein phosphorylation. Is active in nucleus. Orthologous to human ZNF416 (zinc finger protein 416). PHENOTYPE: Homozygous inactivation of this gene exacerbates aortic banding-induced cardiac hypertrophy and fibrosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
