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Protein Coding Gene : Bicra BRD4 interacting chromatin remodeling complex associated protein

Primary Identifier  MGI:2154263 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  243842
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription regulator activator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 12. Orthologous to human BICRA (BRD4 interacting chromatin remodeling complex associated protein).
PHENOTYPE: Mice homozygous for a null allele exhibit lethality between E15 and E16.5 associated with cardiac defects, growth retardation, and edema. Mice heterozygous for the allele exhibit reduced size and weight with reduced growth hormone levels. [provided by MGI curators]
  • synonyms:
  • MGI:5883603,
  • BRD4 interacting chromatin remodeling complex associated protein,
  • glioma tumor suppressor candidate region gene 1,
  • Bicra,
  • Gltscr1

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Disease

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