| Primary Identifier | MGI:3647699 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 666528 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Involved in male meiotic nuclear division; negative regulation of DNA-templated transcription; and positive regulation of DNA-templated transcription. Located in nucleus. Part of histone deacetylase complex. Is expressed in testis. Orthologous to human ZNF541 (zinc finger protein 541). PHENOTYPE: Knock-out males are infertile, with delayed progression from early to mid/late pachynema and no mature spermatozoa in the cauda epididymis. Spermatocytes show abnormal programmed DNA double-strand break repair, impaired crossover formation and resolution, and asynapsis of the XY chromosomes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
