| Primary Identifier | MGI:107996 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 110891 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium:sodium antiporter activity. Involved in several processes, including learning or memory; monoatomic cation transmembrane transport; and regulation of short-term neuronal synaptic plasticity. Acts upstream of or within several processes, including modulation of chemical synaptic transmission; regulation of action potential firing pattern; and response to ischemia. Located in axon terminus; plasma membrane; and postsynaptic density. Is expressed in brain; cerebral cortex; cerebral cortex mantle layer; embryo; and olfactory cortex mantle layer. Orthologous to human SLC8A2 (solute carrier family 8 member A2). PHENOTYPE: The clearance of elevated calcium following depolarization is delayed in homozygous mutant mice, which exhibit enhanced learning and memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
