| Primary Identifier | MGI:2141917 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 101540 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase C binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in positive regulation of macromolecule biosynthetic process and positive regulation of signal transduction. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and vibrissa. Orthologous to human PRKD2 (protein kinase D2). PHENOTYPE: Mice homozygous for a knock-in allele exhibit impaired IgM and IgG1 antigen responses and CD4+ and CD8+ T cell production of IL2 and IFN-gamma in response to TCR stimulation. Mice homozygous for a gene trap allele exhibit normal T lymphocyte maturation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
