Primary Identifier | MGI:109163 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 14709 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within cellular response to pheromone; nose development; and social behavior. Predicted to be part of heterotrimeric G-protein complex. Is expressed in cochlear duct epithelium; retina; and spleen. Orthologous to human GNG8 (G protein subunit gamma 8). PHENOTYPE: Homozygous inactivation of this gene results in a slow but progressive loss of vomeronasal neurons, impairment of specific vomeronasal-mediated behaviors such as maternal and intermale aggression, and reduced physiological responses to pheromonal stimulation. [provided by MGI curators] |