Primary Identifier | MGI:3612184 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 434130 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in microtubule cytoskeleton organization and regulation of mitotic nuclear division. Predicted to be located in several cellular components, including centrosome; cytosol; and nucleoplasm. Predicted to be part of 3M complex. Human ortholog(s) of this gene implicated in 3-M syndrome. Orthologous to human CCDC8 (coiled-coil domain containing 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit perinatal lethality, intrauterine growth restriction, and placental defects. [provided by MGI curators] |