| Primary Identifier | MGI:104296 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 384569 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; regulation of alternative mRNA splicing, via spliceosome; and regulation of axon guidance. Acts upstream of or within regulation of RNA metabolic process. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; olfactory epithelium; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human NOVA2 (NOVA alternative splicing regulator 2). PHENOTYPE: Homozygous mutation of this gene results in postnatal lethality, abolished long term potentiation of the small inhibitory postsynaptic current but not the excitatory postsynaptic current, and no pairing-induced potentiation of small inhibitory postsynatpic currents. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
