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Protein Coding Gene : Meiosin meiosis initiator
Primary Identifier  MGI:3647482 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  243866
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA binding activity and protein dimerization activity. Involved in several processes, including activation of meiosis; cellular response to retinoic acid; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in central nervous system and genitourinary system. Orthologous to human MEIOSIN (meiosis initiator).
PHENOTYPE: Homozygous knockout affects meiosis during spermatogenesis and oocytogenesis and results in male and female sterility. [provided by MGI curators]
  • synonyms:
  • predicted gene, EG243866,
  • Bhmg1,
  • MGI:6441032,
  • EG243866,
  • meiosis initiator,
  • Meiosin,
  • basic helix-loop-helix and HMG-box containing 1,
  • predicted gene 4969,
  • Gm4969,
  • MGI:6389028
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