| Primary Identifier | MGI:1352753 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 381853 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables gastric inhibitory peptide receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and positive regulation of insulin secretion. Acts upstream of or within endocrine pancreas development. Is active in plasma membrane. Is expressed in cortical plate; foregut-midgut junction; neck; and thyroid gland. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; obesity; and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). PHENOTYPE: Homozygous inactivation of this gene results in mild glucose intolerance due to impaired glucose-stimulated insulin secretion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
