| Primary Identifier | MGI:109268 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22323 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable profilin binding activity. Acts upstream of or within actin cytoskeleton organization; axon guidance; and neural tube closure. Located in filopodium; focal adhesion; and lamellipodium. Is expressed in several structures, including adipose tissue; brain; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human VASP (vasodilator stimulated phosphoprotein). PHENOTYPE: Homozygous null mutants exhibit hyperplasia of megakaryocytes, and mutant platelets activated by thrombin display two-fold higher surface expression of P-selectin and fibrinogen binding. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
