Primary Identifier | MGI:1920955 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 232944 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytoskeletal anchor activity. Involved in positive regulation of NLRP3 inflammasome complex assembly. Is active in microtubule organizing center. Orthologous to human MARK4 (microtubule affinity regulating kinase 4). PHENOTYPE: Mice homozygous for a gene trap allele exhibit insulin hypersensitivity and resistance to diet-induced obersity. [provided by MGI curators] |