| Primary Identifier | MGI:1926956 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 63872 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in spermatogenesis. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including bone marrow; central nervous system; early conceptus; gonad; and ureter. Orthologous to human ZNF296 (zinc finger protein 296). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial embryonic lethality, embryonic growth retardation, impaired primordial germ cell development, H3K9 hypermethylation during embryogenesis, small adult gonads, decreased oocyte and sperm counts, and infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
