Primary Identifier | MGI:107741 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 52118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables dynein light chain binding activity. Acts upstream of or within cell migration and cell-cell adhesion. Located in cell surface and plasma membrane. Orthologous to human PVR (PVR cell adhesion molecule). PHENOTYPE: Mice homozygous for one null allele have a reduced antibody response to oral immunization. Mice homozygous for a different null allele exhibit reduced susceptibility to chemically induced colon cancer. [provided by MGI curators] |