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Protein Coding Gene : Nlrp5 NLR family, pyrin domain containing 5

Primary Identifier  MGI:1345193 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  23968
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable tubulin binding activity. Involved in several processes, including cortical granule exocytosis; cytoskeleton organization; and positive regulation of embryonic development. Acts upstream of or within several processes, including embryo implantation; regulation of RNA stability; and regulation of protein stability. Located in several cellular components, including apical cortex; nucleolus; and ooplasm. Part of subcortical maternal complex. Is expressed in early conceptus and ovary. Orthologous to human NLRP5 (NLR family pyrin domain containing 5).
PHENOTYPE: Females lacking this maternal effect gene are sterile. Preimplantation embryos do not develop past the 2-cell stage. [provided by MGI curators]
  • synonyms:
  • Nalp5,
  • Op1,
  • Mater,
  • maternal effect gene,
  • NLR family, pyrin domain containing 5,
  • Nlrp5,
  • ooplasm,
  • NACHT, leucine rich repeat and PYD containing 5

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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