Primary Identifier | MGI:101774 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 12518 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transmembrane signaling receptor activity. Involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and multivesicular body. Part of B cell receptor complex. Is expressed in liver. Human ortholog(s) of this gene implicated in agammaglobulinemia 3. Orthologous to human CD79A (CD79a molecule). PHENOTYPE: Homozygotes for targeted null mutations exhibit arrested development of B cells at the pro-B cell stage due to diminished signaling of the B cell receptor. [provided by MGI curators] |