| Primary Identifier | MGI:101897 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 18987 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and spermidine transmembrane transporter activity. Involved in cellular response to virus; positive regulation of macromolecule biosynthetic process; and spermidine transport. Acts upstream of or within cell maturation; mature B cell differentiation; and positive regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; nervous system; sensory organ; and thymus. Orthologous to human POU2F2 (POU class 2 homeobox 2). PHENOTYPE: Homozygous inactivation of this locus results in failed B cell maturation and death within hours of birth. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
