Primary Identifier | MGI:108414 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 18476 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity; platelet-activating factor acetyltransferase activity; and protein dimerization activity. Acts upstream of or within spermatogenesis. Located in cytoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human PAFAH1B3 (platelet activating factor acetylhydrolase 1b catalytic subunit 3). PHENOTYPE: Homozygous null mice of both sexes are viable and fertile. However, in combination with homozygous disruptions in Pafah1b2, males become infertile. [provided by MGI curators] |