Primary Identifier | MGI:1347246 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 26367 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein dimerization activity. Acts upstream of or within energy homeostasis; negative regulation of brown fat cell proliferation; and negative regulation of feeding behavior. Located in cell surface. Is expressed in metanephros; spleen; and testis. Orthologous to several human genes including CEACAM1 (CEA cell adhesion molecule 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female-specific obesity, disruption in glucose homeostasis, hyperphagia, hyperinsulinemia and decreased energy expenditure. [provided by MGI curators] |