Primary Identifier | MGI:88597 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 13087 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to stilbenoid. Acts upstream of or within cellular response to cadmium ion and heme metabolic process. Predicted to be located in cytoplasmic microtubule. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in alimentary system; liver; nervous system; nose; and respiratory system. Orthologous to several human genes including CYP2A6 (cytochrome P450 family 2 subfamily A member 6). PHENOTYPE: Mice exhibit strain-specific cytochrome activity levels. Mice homozygous for a knock-out allele exhibit slower clearance of nicotine and cotinine. [provided by MGI curators] |