Primary Identifier | MGI:894702 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 18223 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in lateral ventricle development; neuroblast division in subventricular zone; and positive regulation of neurogenesis. Acts upstream of or within adherens junction organization and nervous system development. Located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; peripheral nervous system ganglion; and sensory organ. Orthologous to human NUMBL (NUMB like endocytic adaptor protein). PHENOTYPE: Mice homozygous for a knock-out allele are viable and exhibit no overt phenotypes except for a reduction in female fertility. [provided by MGI curators] |