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Protein Coding Gene : Sertad1 SERTA domain containing 1
Primary Identifier  MGI:1913438 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  55942
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus and sarcoplasm. Is expressed in several structures, including 1st branchial arch; early embryo; genitourinary system; heart; and limb. Orthologous to human SERTAD1 (SERTA domain containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired glucose tolerance and decreased glucose-stimulated insulin secretion associated with decreased islet number and beta cell mass. [provided by MGI curators]
  • synonyms:
  • p34SEI-1,
  • SERTA domain containing 1,
  • Sei-1,
  • 1110032C13Rik,
  • expressed sequence AW456625,
  • AV000455,
  • Sertad1,
  • MGI:2142168,
  • expressed sequence AV000455,
  • MGI:2142231,
  • Trip-Br1,
  • AW456625,
  • RIKEN cDNA 1110032C13 gene
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