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Protein Coding Gene : Map3k10 mitogen-activated protein kinase kinase kinase 10
Primary Identifier  MGI:1346879 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  269881
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein kinase activity and transcription corepressor activity. Acts upstream of or within negative regulation of DNA-templated transcription and protein phosphorylation. Predicted to be active in cytoplasm. Is expressed in brown fat; heart; ovary; renal vasculature; and testis. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10).
PHENOTYPE: Mice homozygous for a null allele exhibit normal development, reproduction and lifespan. [provided by MGI curators]
  • synonyms:
  • cDNA sequence BC028668,
  • mitogen-activated protein kinase kinase kinase 10,
  • BC028668,
  • MGI:2652863,
  • Map3k10,
  • mixed lineage kinase 2 (tyrosine and serine/threonine specificity),
  • Mlk2,
  • mixed lineage kinase 2,
  • serine/threonine kinase,
  • BC046514,
  • MGI:2652864,
  • MKN28 derived nonreceptor_type,
  • MKN28 kinase,
  • cDNA sequence BC046514,
  • MGI:1336178
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