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Protein Coding Gene : Pak4 p21 (RAC1) activated kinase 4
Primary Identifier  MGI:1917834 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  70584
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein kinase activity. Acts upstream of or within cellular response to organic cyclic compound and dendritic spine development. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PAK4 (p21 (RAC1) activated kinase 4).
PHENOTYPE: Homozygous null mice die at midgestation exhibiting heart defects as well as impaired neuronal development and yolk sac vasculature. [provided by MGI curators]
  • synonyms:
  • AW555722,
  • expressed sequence AW555722,
  • Pak4,
  • MGI:2142263,
  • RIKEN cDNA 5730488L07 gene,
  • p21 (RAC1) activated kinase 4,
  • mKIAA1142,
  • 5730488L07Rik
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