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Protein Coding Gene : Gmfg glia maturation factor, gamma
Primary Identifier  MGI:1927135 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  63986
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable Arp2/3 complex binding activity. Acts upstream of or within actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be active in cortical actin cytoskeleton. Is expressed in several structures, including brain; cardiovascular system; gut; hemolymphoid system; and yolk sac. Orthologous to human GMFG (glia maturation factor gamma).
PHENOTYPE: Mice homozygous for a null mutation display impaired marginal zone B cell functions. [provided by MGI curators]
  • synonyms:
  • MGI:1923721,
  • RIKEN cDNA 0610039G16 gene,
  • MGI:1914927,
  • expressed sequence AI324845,
  • MGI:2141393,
  • 2310057N07Rik,
  • AI324845,
  • Gmfg,
  • RIKEN cDNA 2310057N07 gene,
  • glia maturation factor, gamma,
  • 0610039G16Rik
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Genes/Features --> Phenotypes (MP terms)

Disease

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