| Primary Identifier | MGI:2181461 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 243897 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and ubiquitin protein ligase binding activity. Involved in gamete generation. Acts upstream of or within double-strand break repair; embryo implantation; and protein localization. Located in perinuclear region of cytoplasm. Is expressed in brain; early conceptus; eye; gonad; and metanephros. Human ortholog(s) of this gene implicated in spermatogenic failure 69. Orthologous to human GGN (gametogenetin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit early embryonic lethality. Mice heterozygous for this allele exhibit impaired double-strand break repair in spermatocytes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
