Primary Identifier | MGI:1891291 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 52150 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Acts upstream of or within negative regulation of systemic arterial blood pressure and regulation of resting membrane potential. Predicted to be active in plasma membrane. Is expressed in heart; liver left lobe; and liver right lobe. Orthologous to human KCNK6 (potassium two pore domain channel subfamily K member 6). PHENOTYPE: Male mice homozygous for a knock-out allele exhibit vascular dysfunction and hypertension. [provided by MGI curators] |