Primary Identifier | MGI:1931139 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 68458 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase inhibitor activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in cytoplasm. Is expressed in several structures, including cardiovascular system; embryo endoderm; gut; nervous system; and respiratory system. Orthologous to human PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A). PHENOTYPE: Mice homozygous for a null allele show abnormal arterial contraction responses and resistance to high fat diet induced hypertension but not obesity. [provided by MGI curators] |