Primary Identifier | MGI:1929093 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 56189 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; renal cortex; and sensory organ. Orthologous to human PRODH2 (proline dehydrogenase 2). PHENOTYPE: Mice lacking the full-length protein exhibit increased circulating hydroxyproline level and elevated urinary hydroxyproline excretion levels. [provided by MGI curators] |