Primary Identifier | MGI:2673998 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233071 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Involved in regulation of postsynapse assembly. Located in cytoplasm and plasma membrane. Is active in glutamatergic synapse. Is expressed in brain; parathyroid gland; peripheral nervous system; and prostate gland. Orthologous to human ARHGAP33 (Rho GTPase activating protein 33). PHENOTYPE: Mice homozygous for a null mutation display region specific thinning of the cerebral cortex with reduced dendritic complexity. [provided by MGI curators] |