| Primary Identifier | MGI:2685325 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 243912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including protein homodimerization activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including negative regulation of cardiac muscle cell apoptotic process; positive regulation of angiogenesis; and protein folding. Predicted to be located in several cellular components, including cytosol; mitochondrion; and nuclear speck. Predicted to be active in cytoplasm and nucleus. Is expressed in brain subventricular zone; lung; retina inner nuclear layer; retina outer nuclear layer; and smooth muscle tissue. Orthologous to human HSPB6 (heat shock protein family B (small) member 6). PHENOTYPE: Mice homozygous for a knock-out allele show increased rates of mortality and ascending aortic rupture in a BAPN-induced thoracic aortic aneurysm and dissection model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
