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Protein Coding Gene : Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Primary Identifier  MGI:95653 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  14447
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Is expressed in cerebral cortex; heart; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic).
PHENOTYPE: Homozygous null mice display male infertility and asthenozoospermia. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-9981,
  • Gapdhs,
  • Gapds,
  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic,
  • MGD-MRK-9980,
  • Gapd-s

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For