Primary Identifier | MGI:2446326 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 282619 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Located in cytoplasm. Is expressed in several structures, including alimentary system; nose; and skin. Orthologous to human SBSN (suprabasin). PHENOTYPE: Mice homozygous for a null allele exhibit impaired embryo barrier function in embryos; scarce, immature, and fragile stratum corneum; increased nickel serum levels following loading; and increased contact hypersensitivity in response to nickel loading. [provided by MGI curators] |