Primary Identifier | MGI:104982 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 12611 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in hemopoiesis; natural killer cell mediated cytotoxicity; and regulation of gene expression. Acts upstream of or within mRNA metabolic process. Located in nucleus. Is expressed in several structures, including blood; central nervous system; genitourinary system; retina; and yolk sac. Orthologous to human CEBPG (CCAAT enhancer binding protein gamma). PHENOTYPE: Homozygous mutation of this gene results in impaired natural killer cell cytotoxic activity and IFN-gamma production. [provided by MGI curators] |