| Primary Identifier | MGI:3584516 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 435965 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in negative regulation of fat cell differentiation; positive regulation of osteoblast differentiation; and regulation of gene expression. Predicted to be active in plasma membrane. Orthologous to human LRP3 (LDL receptor related protein 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit accelerated post-injury osteoarthritis and senescence-induced osteoarthritis development. Mice show reduced weight gain and increased total cholesterol serum levels on a high cholesterol diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
