Primary Identifier | MGI:1931250 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72310 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including CD4-positive, alpha-beta T cell activation; defense response to other organism; and granzyme-mediated programmed cell death signaling pathway. Located in cytolytic granule. Is expressed in ductus deferens; epididymis; esophagus; prostate gland; and thymus primordium. Orthologous to human NKG7 (natural killer cell granule protein 7). PHENOTYPE: Homozygous knockout leads to a reduced inflammatory response to parasitic infection or injected tumor cells. [provided by MGI curators] |