Primary Identifier | MGI:3644563 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 100503991 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable acid phosphatase activity; protein tyrosine phosphatase activity; and receptor tyrosine kinase binding activity. Predicted to be involved in several processes, including negative regulation of ERBB4 signaling pathway; negative regulation of protein metabolic process; and regulation of neuronal synaptic plasticity. Predicted to be located in membrane. Predicted to be active in lysosome and postsynaptic membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Orthologous to human ACP4 (acid phosphatase 4). PHENOTYPE: Mice homozygous for an endonuclease-mediated mutation exhibit chalky-white enamel. [provided by MGI curators] |