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Protein Coding Gene : Lrrc4b leucine rich repeat containing 4B
Primary Identifier  MGI:3027390 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  272381
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables signaling receptor binding activity. Involved in positive regulation of synapse assembly. Located in cerebellar mossy fiber. Is expressed in several structures, including branchial arch; central nervous system; heart; sensory organ; and sympathetic nervous system. Orthologous to human LRRC4B (leucine rich repeat containing 4B).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired brain development and impaired long-term depression, and locomotive and cognitive behaviors in a background strain manner. [provided by MGI curators]
  • synonyms:
  • Ngl3,
  • leucine rich repeat containing 4B,
  • NGL-3,
  • Lrrc4b,
  • leucine-rich repeats and immunoglobulin-like domains 4,
  • Lrig4
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