Primary Identifier | MGI:1347560 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 22116 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity. Located in centriole. Is expressed in seminiferous tubule; spermatid; and testis. Orthologous to human TSKS (testis specific serine kinase substrate). PHENOTYPE: Mice homozygous for a null allele exhibit male sterility, low sperm motility, abnormalities in sperm head, midpiece and mitochondrial sheath morphology, and a spermiation defect associated with impaired elimination of spermatid cytoplasm, excess residual cytoplasm, and increased apoptosis in spermatozoa. [provided by MGI curators] |