Primary Identifier | MGI:1920211 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72961 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables L-glutamate uniporter activity and inorganic anion transmembrane transporter activity. Involved in several processes, including L-glutamate transmembrane transport; neurotransmitter loading into synaptic vesicle; and phosphate ion transport. Acts upstream of or within several processes, including chemical synaptic transmission; long-term memory; and sequestering of neurotransmitter. Located in several cellular components, including cerebellar mossy fiber; presynaptic active zone; and synaptic vesicle membrane. Is expressed in several structures, including brain; retina layer; and spinal cord dorsal horn. Orthologous to human SLC17A7 (solute carrier family 17 member 7). PHENOTYPE: Homozygous mutant mice are small and fail to thrive by 3-4 weeks of age. Abnormal excitatory post synaptic potential and currents. [provided by MGI curators] |